Norris has stepped up from Formula 2 last season after finishing second in the Championship, replacing Stoffel Vandoorne and driving alongside Carlos Sainz this year.
He heads to Australia, a venue he is yet to have driven on after only experiencing it through simulations, after the two weeks of testing in Barcelona learning and preparing with the team and the car.
Norris said (quoted by F1i.com): "This weekend marks the start of an important new chapter in my career.
"I'm excited to be making my Formula 1 debut and ready for the challenges that lie ahead.
"There are plenty of new procedures for me to get used to as I step up from F2, so the two weeks at pre-season testing were valuable as they allowed me to fully prepare for this weekend.
"This will be my first-time visiting Australia, so it'll be cool to see a new country.
"I've spent a lot of time preparing for the race in the simulator back at the factory; there are a few new circuits for me to learn this year.
"Since leaving Barcelona, I've spent a lot of time working with engineers and making my final preparations before taking to the track in Melbourne.
"I feel ready and I'm looking forward to working with Carlos and the team as we take on the 2019 season together."